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ea0011p837 | Thyroid | ECE2006

The role of autoimmunity and thyroid function on pregnancy outcomes in euthyroid women with autoimmune disease undergoing assisted reproduction

Negro R , Formoso G , Coppola L , Presicce G , Mangieri T , Pezzarossa A , Dazzi D

Context: Euthyroid women positive for thyroid antibodies are prone to develop subclinical/overt hypothyroidism during gestation and seem to suffer from a poor outcome.Objective: Assessing if patients with autoimmune thyroid disease undergoing Assisted Reproduction Technologies (ART) are afflicted by poor pregnancy and/or delivery rate and if the outcome is conditioned by pre-ART thyroid status.Design: Prospective study since Januar...

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ea0029p1652 | Thyroid (non-cancer) | ICEECE2012

Proptosis reduction in patients with Graves’ orbitopaty (go) at 12 weeks after intravenous steroid therapy is associated to disease inactivation

Vannucchi G. , Campi I. , Covelli D. , Curro N. , Cirello V. , Dazzi D. , Beck-Peccoz P. , Salvi M.

We have retrospectively studied the clinical outcome of 58 patients (14 men and 44 women) with autoimmune thyroid disease and active GO, treated with high dose intravenous methylprednisolone (MP; cumulative dose 7.5 g). Ophthalmological assessment was performed at baseline and at 6, 12 and 2430 weeks after the first MP infusion. In 43/58 patients we have also studied NR3C1gene polymorphism, which has been associated to different sensitivity to steroids. The therapeutic o...

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Endocrine Abstracts

The role of autoimmunity and thyroid function on pregnancy outcomes in euthyroid women with autoimmune disease undergoing assisted reproduction

Proptosis reduction in patients with Graves’ orbitopaty (go) at 12 weeks after intravenous steroid therapy is associated to disease inactivation

BiosciAbstracts